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As we discussed above, glutathione reduced ethyl ester is definitely the form youll want to use for cell culture as it has a much higher cellular uptake (Levy et al, 1993)

[DOI] [PubMed] [Google Scholar] 416.Beuter W., Cojocel C., Mller W., Donaubauer H.H., Mayer D

For these experiments, we used the biochemically amenable fragment of NCOA4 383522 (Fig 1A and B) that is sufficient to bind ferritin (Hoelzgen et al, 2024), but lacks both the putative coiled-coil domain and domains that overlap with the -isoform, which does not bind ferritin or support ferritinophagy (Mancias et al, 2015)

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