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J Allergy Clin Immunol

When patients ask me does laser lipo work compared to other methods, I explain that it addresses both fat reduction and skin laxity simultaneously, which is why its often our preferred approach for comprehensive body contouring. When compared to cryolipolysis (fat freezing), the differences are quite striking

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A 2021 peer-reviewed review of NNMT in obesity and type 2 diabetes states explicitly that 'clinical trials targeting NNMT have not been reported' meaning every quantitative efficacy figure available for this compound comes from mice, and there is currently zero published human efficacy data