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Elevated numbers of Th17 cells and increased levels of Th17-related cytokines, including IL-17 and IL-22, have been reported in HT, correlating with disease severity and autoantibody titers

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Although immune dysfunction is clear in ME/CFS, further studies using defined cohorts, standardised assays, and new technologies are required to determine specific patterns (488), contradicting the hypothesis that ME/CFS could be caused by a clearance failure of the pathogenic microbe (99, 107)

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