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Astrocytes, the predominant glial cells in the central nervous system (CNS), play a crucial role in regulating energy metabolism, supporting neuronal and synaptic activity, and maintaining the proper function and integrity of the blood-brain barrier (BBB) [29, 30]

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A Phase I clinical trial established the dosing range of 0.01 to 0.03 mg/kg body weight, with significant tanning after five doses (Dorr et al

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