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Unlike other members of the alcohol dehydrogenase family, GSNO reductase has little variation in expression across tissues and is the only alcohol dehydrogenase expressed in human and rodent brain, an organ known to be highly regulated by NO- and S-nitrosothiol-dependent signals [70]

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A novel NFKBIA variant substituting serine 36 of IB causes immunodeficiency with warts, bronchiectasis and juvenile rheumatoid arthritis in the absence of ectodermal dysplasia