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Functional anti-aging components in foods include substances involved in the synthesis and metabolism of skin components (e.g., protein peptides and essential fatty acids), as well as substances that inhibit the degradation of skin components and maintain their structural integrity (e.g., substances that regulate the expression of enzymes, such as matrix metalloproteinases (MMPs) and activated protein 1 (AP-1)) [205]

Percentage data were analysed using the chi-square test

For most enzyme inducers, hyperplasia is transient and may require specific DNA labeling studies or immunohistochemical stains to clearly identify its occurrence

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DOI: 10.2147/NDT.S212361 12