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Macrophage membrane modified baicalin liposomes improve brain targeting for alleviating cerebral ischemia reperfusion injury

Acknowledgements This study was supported in part by a Grant-in-Aid for Scientific Research from the Ministry of Education, Science and Culture of Japan, Japan Heart Foundation Grant for Research on Hypertension and Metabolism, and a Grant for Research Foundation for Community Medicine

These changes lead to progressive symptoms, with both increasing frequency and severity of vertigo and hearing loss

Despite low CNS penetration, some studies report detectable levels in the brain, supporting its potential for systemic biological effects without significant accumulation (Jzwiak et al