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This damage can result from disturbances to many pathways, including the polyol pathway, protein kinase C (PKC) pathway, and others (as shown in Figure 3 )

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( Collagenase VII-Induced Intracerebral Hemorrhage Model Intracerebral hemorrhage was induced via stereotactic administration of 0.25 U/l bacterial collagenase type VII (Sigma, United States), as Rosenberg described ( Brain Water Content Rats were anesthetized, and the brains were collected 3 days following ICH

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