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10.1016/j.jaip.2012.09.003 19

Lipid metabolism is abnormal in rapidly proliferating cancer cells

Cabrera-Lopez C

Initially identified as nine fundamental biological drivers of aging (13), the list has been updated to include twelve hallmarks: genomic instability, telomere attrition, epigenetic alterations, loss of proteostasis, disabled macroautophagy, deregulated nutrient-sensing, mitochondrial dysfunction, cellular senescence, stem cell exhaustion, altered intercellular communication, chronic inflammation, and dysbiosis (14)