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The trial protocol was approved by the Madrid Region Clinical Research Ethics Committee ( Comit tico de Investigacin Clnica Regional de la Comunidad de Madrid ) on February 8 th 2011, and has been registered with ClinicalTrials.gov number NCT 01476007, and under EUDRACT number 2010-024129-20 [Oral Versus Intramuscular Cobalamin to treat Cobalamin Deficiency: Noninferiority randomised controlled trial, pragmatic and multi-center in the primary healthcare setting (OB12 project)]

The dissolving nature of Juvederm is what allows us to dissolve it with an enzyme if there is a complication or undesired result, and many patients very much like having this option available to them

It reduces sneezing, congestion, nasal drip with people with allergic rhinitis and reduces blood pressure