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Correlation analysis and statistical analysis Statistical analysis and graphing were performed by R-v3.6.1 software, SPSS software version 21.0, and Origin 2022 software for correlation plot analysis, inertia analysis, differential metabolite-differential microbial string plots, and differential metabolite-differential microbial network plots

82 EndMT plays a critical role in the development of diabetic atherosclerosis and is driven by various atherogenic stimuli, including hyperglycemia, AGEs, and oxidized low-density lipoprotein (ox-LDL)