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Chen X, Xie N, Feng L, Huang Y, Wu Y, Zhu H, Tang J, Zhang Y

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Interestingly, the direct infusion of an anti-APP antibody into the affected brain region following TBI in rats resulted in a reduction in neuronal loss, less astrocyte activation, a smaller region of brain damage and less behavioral impairment than was evident in vehicle treated TBI animals [94], supporting a reduction in APP as a therapeutic strategy worth investigating

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101 NassireslamiE.NikbinP.AminiE.PayandemehrB.ShaerzadehF.KhodagholiF.et al (2016)