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The purpose of this adipose tissue catalase upregulation in obesity is not conclusively known, but, at least in animal models, adipose tissue catalase plays an important role not only in antioxidant defense but also in protection against obesity-associated inflammation [32]

Concato et al., Randomized, Controlled Trials, Observational Studies, and the Hierarchy of Research Designs, New England Journal of Medicine, doi:10.1056/NEJM200006223422507

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First, the high water content of hydrogels gives these materials the flexibility to mimic natural organization