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The most common benzoic acid derivatives comprise gallic acid mostly present in tea, mango, rhubarb, soy, tannic acid, protocatechuic acid, and capsaicin

However, the application of fosfomycin faces a central paradox: despite being a potent bactericide with good safety, the rapid development of resistance during both in vitro and in vivo monotherapy severely restricts its clinical utility (Silver, 2017)

Despite the known direct association of p300 with NRF2, p300 is only detected at a small subset of group II gene promoters despite high occupancy of NRF2

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