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doi: 10.1152/japplphysiol.00071.2011

Through the regulation of glutamate and GABA, glutamine within the CNS plays an integral role in many aspects of neurobiology and as such disturbances in glutamine metabolism and/or transport have been implicated in a range of pathologies ranging from chronic stress, epilepsy, hepatic encephalopathy, manganese encephalopathy, neurodegenerative disorders and metabolic disease (Reference Huang, Liu and Yin54,Reference Ivens, Caliskan and Papageorgiou55)

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Genomics Genomics is the study of an organism's genome structure and function, and its relationship to phenotype

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