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Significantly reduced GPX1 and SELENOP protein expression in the liver compared to the high-selenium alone group and the high-selenium + serine group

Nat Commun (2017) 8(1):14630

While the agency has cited "significant safety risks" as the rationale behind this categorization, it has not divulged the specific methodology or details pertaining to the identified risks

On the other hand, given the increasing aging of the population, a continuous increase in cataract patients is expected in the coming years, leading to a significant economic cost for public health systems

Consistent with this, the release of BDNF has been reported to depend on Ca 2+ -influx via L-type voltage-gated calcium channels (VGCC) in primary cultures of hippocampal neurons from embryonic or newborn rats and mice (Kolarow et al