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pmid:21567682 28

These mixed responses cannot be generalized, but the fact that a subset experience real improvement makes this an important signal to investigate

Induced/reduced peaks were determined by overlapping peaksets with bedtools intersect 108 , after which gene TSSs overlapping peaks (100 kb, +50 kb) were determined with bedtools closest 108 , and motif enrichment was obtained with findMotifsGenome.pl script from the HOMER v5.1 package 110