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A recent study showed that the HSV-1 host/pathogen interactome is highly concentrated in susceptibility genes for neurological disorders, primarily for MS, with enrichment values at 4-fold, suggesting that HSV-1 may contribute to several diseases in a gene-dependent manner by modulating essential pathways involved in the onset or severity of this neurodegenerative disease (Carter, On the other hand, microorganisms may also contribute to the pathogenesis of MS by inducing the activation and clonal expansion of self-reactive lymphocytes through molecular mimicry (Wucherpfennig and Strominger, 1995)

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Conversely, the MCNs/Ln/GD/FR(IV) group showed reduced green fluorescence in the non-tumor area, indicating minimal tissue damage

Molecules 27 (7), 2114