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Heteroaryl groups include, but are not limited to, pyrrolyl, pyrazolyl, triazolyl, tetrazolyl, oxazolyl, isoxazolyl, thiazolyl, pyridinyl, pyridazinyl, pyrimidinyl, pyrazinyl, thiophenyl, benzothiophenyl, furanyl, benzofuranyl, indolyl, azaindolyl (pyrrolopyridinyl), indazolyl, benzimidazolyl, pyrazolopyridinyl, triazolopyridinyl, benzotriazolyl, benzoxazolyl, benzothiazolyl, imidazopyridinyl, isoxazolopyridinylxanthinyl, guaninyl, quinolinyl, isoquinolinyl, tetrahydroquinolinyl, quinoxaliny halo or halogen is intended to include F, Cl, Br, and I

However, substituting the ethyl ester with an amide group, as in SRS9-11 (EC50 = 950 nM), resulted in a notable reduction in activity, though this finding was later contradicted by Hofmans et al

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IL-6 in inflammation, autoimmunity and cancer

TERF1 may be a linker in ET and osmotic signaling pathways (Huang et al., 2004)