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Some people might refer to these compounds as synthetic cannabinoids or synthetic cannabinoids that mimic the effects of THC (which is how the World Anti-Doping Agency (WADA) refers to these compounds on the WADA Prohibited List)

It is hypothesised that these mechanisms occur in a spiralling, progressive way, toppling the hosts homeostatic equilibrium ( Gut dysbiosis ME/CFS patients often have gastrointestinal (GI) symptoms (189) with gut inflammation (190), gut microbiome dysbiosis (191) and changes in the gut microbiome (191, 192)

Instead, they bind to receptors on the surface of target cells to trigger a cascade of events inside the cell

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10.1002/hep.31914 48 KangY.KangX.YangH.LiuH.YangX.LiuQ.et al (2022)