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43 TNFstimulated gene6 (TSG6), a protein secreted during inflammation, has been implicated to have antiinflammatory and tissueprotective properties

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Deficiency may cause fatigue, neurological symptoms, and cognitive changes, with treatment often improving symptoms when deficiency is present

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To calculate the Part D drug inflation rebate consistent with section 1860D-14B(b)(1) of the Act, we proposed at 428.201(a)(1) to codify the calculation methodology described in section 40 of the revised Medicare Part D Drug Inflation Rebate Guidance, which provides that the total Part D drug inflation rebate amount is equal to the per unit Part D drug inflation rebate amount, as determined under 428.202(a), multiplied by the total number of units of a Part D rebatable drug dispensed under Part D and covered by Part D plan sponsors, as determined in accordance with 428.203