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Description

Dysregulation of alveolar macrophage PPAR, NADPH oxidases, and TGF1 in otherwise healthy HIV-infected individuals

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Wang L, Brennan M, Li S, et al

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BCAA oxidation enzymes are present in the nuclei of PanIN lesions and PDA patient tumors The unexpected presence of the BCAA catabolic pathway in the nuclei of murine PDA cells prompted us to investigate the localization of enzymes of this pathway in mouse genetic PDA models and human PDA samples

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Second, host-related factors such as species, genetic background, and disease state can influence probiotic efficacy

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