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10.1152/ajpcell.00046.2015 Am J Physiol Cell Physiol

Food Chem Toxicol Int J Publ Br Ind Biol Res Assoc

(53) employed mathematical modeling to study the heterogeneity of drug resistance mutations in patients with metastatic cancer, finding that obvious mutation heterogeneity exists in all metastatic lesions, and these mutations cause resistance to drugs