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The presence of multiple RCD pathways ensures that when one death pathway is suppressed, others can compensate and function to maintain tissue and organ homeostasis

(91), who investigated the effect of NaHS on testicular dysfunction induced by cyclophosphamide, a drug used to treat many malignancies but which can also cause serious side effects such as hemorrhagic cystitis and male infertility

Crit Rev Immunol

Also, -KG downregulated the mTORC1 pathway and instead induced nuclear PPAR as driver of FAO gene expression (Liu et al., 2017)

In general, cancer disease has a better prognosis and response to treatment when neoplastic cells display higher degrees of differentiation