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10.1186/1477-3155-12-15 183 PerezL.ScarcelloE.IbouraadatenS.YakoubY.LeinardiR.AmbroiseJ.et al (2021)

Yang et al (283), discovered that the dual-targeting of IL-6, which stimulates different macrophages activation in GBM, and CD40 may help in reversing tumor immunosuppression mediated by macrophages thus informing the immunotherapy based on T-cells against GBM

Assays performed with leaf extracts of these lines indicated that GSAAT(C138S) and GSAAT(C396) are weakly stimulated by the addition of DTT (by up to 20% compared to their UT samples)