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Several ongoing clinical trials are combining these glutamine-altering drugs with immune checkpoint inhibitors or with inhibitors of receptor tyrosine kinase signaling, the major signal that tells cells to acquire nutrients and grow

10.1007/s10616-024-00666-7 60 GrskaA.TrubalskiM.BorowskiB.BrachetA.SzymaczykS.MarkiewiczR

Wadhwa R, Wang X, Baladandayuthapani V, Liu B, Shiozaki H, Shimodaira Y, Lin Q, Elimova E, Hofstetter WL, Swisher SG , Rice DC, Maru DM, Kalhor N, Bhutani MS, Weston B, Lee JH, Skinner HD, Scott AW, Kaya DM, Harada K, Berry D, Song S, Ajani JA

Oxidized Low-Density Lipoprotein Accumulation in Macrophages Impairs Lipopolysaccharide-Induced Activation of AKT2, ATP Citrate Lyase, Acetyl-Coenzyme A Production, and Inflammatory Gene H3K27 Acetylation

As the result, the maximum number of core regions listed in this summary is 15