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It is interesting to observe that the protein levels of LXR and its target gene, ABCA1 , are downregulated in primary colon cancer specimens and in synchronous liver metastases (Lo Sasso et al., 2013)

Advanced magnetic resonance imaging in glioblastoma: a review

In this regard, it can be noted that transcription of the gdhA gene initiates from two promoters, one weak, constitutively expressed, called gdhA P1, and another, more potent, called gdhA P2, transactivated by GdhR, a transcriptional regulator whose DNA binding is inhibited by -ketoglutarate (Pagliarulo et al., 2004)

To measure their actual stiffness, the gels were immersed in PBS and force was measured on a NanoWizard three NanoOptics atomic force microscope (JPK Instruments, Berlin, Germany)

doi: 10.1016/j.ijid.2021.04.035