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doi: 10.1189/jlb.2AB0514-273RR 64 GerrietsVAKishtonRJJohnsonMOCohenSSiskaPJNicholsAGet al

10.2741/3064 Front

These mice exhibited significantly reduced skeletal muscle endurance and attenuated hyperemic response to acetylcholine, an endothelium-dependent vasodilator

These models are capable of more effectively recreating the multicellular architecture and cell-to-cell interactions, being a more reliable and versatile technique for the study of several complex mechanisms of disease [89]