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This large size can impede diffusion within the dense tumor extracellular matrix, frequently restricting accumulation to perivascular regions and preventing penetration into hypoxic, acidic tumor cores, a limitation that contributes to heterogeneous therapeutic responses [221]

Nitration of glutamate transporters can inhibit their function, increasing the likelihood of excitotoxicity (Chen et al., 2010)

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1997) przekadao si to na czysty profil GH-sekretagogiczny: uwalnianie hormonu wzrostu bez istotnego podniesienia kortyzolu i prolaktyny

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