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To this end, animal models, particularly genetic mouse models, have provided critical insights into genetic and molecular profiles of IVD development

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Symptoms of vitamin B6 deficiency include: acne, hair loss, normocytic anemia, loss of appetite, mouth ulcers, seizures, cognitive changes, rashes, cheilitis, a swollen tongue (glossitis), depression, nervousness, irritability, dizziness, numbness, pins and needles, electric shock sensations, sleepiness and fatigue, weakness, poor wound healing, joint pain, flaky skin, hearing problems, and growth retardation