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Description

Key pro-inflammatory mediatorssuch as IL6, TNF, and COX2activate survival pathways (e.g., JAK/STAT, NFB) promoting proliferation, angiogenesis, and immune evasion

doi: 10.4049/jimmunol.0802999 40 ZhangYLiYZhouLYuanXWangYDengQet al

J Biol Chem 276:1893418940

Various neural and humoral factors, such as autonomic ganglion, bradykinin, and adenosine, have been implicated in the pathophysiologic mechanisms of remote ischemic preconditioning [62]