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However, the optimal dosage, administration route and long-term safety of NADPH precursors remain unvalidated in large animal models, and the crosstalk of NADPH metabolism, iron homeostasis and retinal inflammation is poorly understood, limiting clinical translation of NADPH-targeted therapies and requiring further investigation

MATERIALS AND METHODS General procedures The published protocols (1) were followed, with exceptions noted below

This observation was consistent with the fluorescence measurements, underscoring the therapeutic advantage of MDMOC

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Duodenal bacterial proteolytic activity determines sensitivity to dietary antigen through protease-activated receptor-2