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Here, we describe the role of NRF2 in the common hallmarks of neurodegeneration, review the current pharmacological interventions and their challenges in activating the NRF2 pathway, and present alternative therapeutic approaches for disease modification

Folic acid-fortified breakfast cereals, many of which contain 400 mcg per serving, are an alternative option for individuals who are unable or unwilling to consume folic acid tablets (Cox & Phelan, 2008)

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(2244:) ghrelin precursor [Homo sapiens]

Meanwhile, increased degradation of CD36 due to enhanced ubiquitination of CD36 by platelet-derived EVs inhibit cholesterol recruitment in macrophages [106] (Fig