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HE staining analysis results exhibited that the COPD rats treated with NAC and oe-VWF had less inflammatory cell infiltration, less destruction of the alveolar septum, and complete columnar epithelial cells compared with those treated with NAC and oe-NC, while opposite trends were noted in the presence of NAC + oe-VWF compared with oe-VWF alone (Fig

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Each variant received a TP53 enrichment score wherein a negative TP53 enrichment score is representative of a variant which was depleted in the treatment population as compared to the untreated control population (Fig

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