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10.3390/nu16162753 30 FerreiraB.MendesF.OsrioN.CaseiroA.GabrielA.ValadoA

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A recent meta-GWAS study showed that individuals in the top decile of genetic risk (across all loci of PNPLA3, TM6SF2, and MBOAT7) have a significantly elevated risk of MASLD, cirrhosis, and HCC (OR up to 6-fold) [280]