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Deng R, Cui C, Remedios LW, Bao S, Womick RM, Chiron S, Li J, Roland JT, Lau KS, Liu Q, Wilson KT, Wang Y, Coburn LA , Landman BA, Huo Y

Assessing glucose homeostasis, employing the oral glucose tolerance test (oGTT), showed an impaired glucose metabolism in WT relative to symptomatic aged 5xFAD mice (Supplementary Fig

This was characterized by increased activity of fosab neuronal markers and cumulative motor responses, and impaired GABA-glutamate balance, revealing GAs potential neurotoxicity ( Furthermore, GA (25100 M) reduced the cell viability of mouse spermatogonia, mouse spermatocytes, and mouse Sertoli cells, suggesting that GA might have adverse effects on male reproductive health, which was associated with an increase in H2O2 levels (Park et al., 2008)