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Those following a vegan diet or with a history of heavy alcohol consumption might need higher B12 supplement dosages

Emerging multi-stakeholder consortia that include academia, industry, and regulators are beginning to shape this landscape by sharing data, defining best practices, and establishing reference materials for evaluation

doi: 10.4049/jimmunol.2200144 156 ChuPGArberDA

In general, a urine flow rate of less than 1 L per day increases the risk of stone formation (Curhan 2012), and guidelines for people with a history of kidney stones include the recommendation to maintain their urine output above 2 L per day (Antonelli 2015)