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2c,d, Extended Data Fig

Documentation of research use and maintenance of records is essential for regulatory compliance and research integrity

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Among the kynurenines, only the basal concentration of HK increases in plasma in vitamin B6-deficient subjects, which probably reflects that its removal but not formation involve PLP-dependent enzymes (Figure 2)

Bottom line from the research: creatine won't directly cause fat loss, but it's a powerful tool for improving body composition when combined with proper training and nutrition