glutathione can cause cancer Application of depletion in therapy: Enhanced ROS-based therapy, ferroptosis, and chemotherapy Role of Glutathione in Cancer:

Nanotechnology-enabled biosensors: a review of fundamentals, design principles, materials, and applications

Glutathione is a tripeptide that is synthesized by forming one peptide bond between the gamma-carboxyl group of glutamate and the amino group of cysteine (forming gamma- glutamyl cysteine), and then by forming a second peptide bond between the carboxyl group of cysteine and the amino group of glycine

Prognosis A long-term follow up study of 28 patients with glutathione synthetase deficiency has showed that the factors most predictive of survival and long-term outcome are early diagnosis, correction of acidosis and early supplementation with vitamin C and vitamin E [19]

Higher GSSG is often consistent with oxidation, but GSSG is highly sensitive to preanalytical error

[DOI] [PMC free article] [PubMed] [Google Scholar] 134.Wills A