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This complex attaches to the regulatory region of DNA called the antioxidant response element (ARE), leading to the expression of antioxidant enzymes such as NAD(P)H quinone oxidoreductase 1 (NQO1) and HO-1

Magon NJ, Turner R, Gearry RB et al (2015) Oxidation of calprotectin by hypochlorous acid prevents chelation of essential metal ions and allows bacterial growth: relevance to infections in cystic fibrosis