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One of the main sites of absorption is the red blood cells

Extracellular Acidification Lactate, the final product of glycolysis, is released from cells together with H + ions by means of monocarboxylate transporters and hydrogen ion pumps, and the excess carbon dioxide produced in the process of mitochondrial metabolism diffuses into the extracellular space and is then converted into H + and HCO3- by carbonic anhydrase (265)

Importantly, successful clinical translation of ferroptosis-targeted therapies will hinge not only on developing effective and safe drugs, but also on our ability to identify patients most likely to benefit and to monitor therapeutic responses in real time