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Lack of insulin receptor signaling in Leprechaunism may result in the rare event of an alive but severely small for gestational age baby that will only survive if treated with recombinant-IGF-1 to substitute inulin receptor signaling with IGF1R signaling via their common intracellular pathways

To identify the specific lipases responsible, we utilized inhibitors for the main cytosolic lipases: ATGL, HSL, and MAGL (Fig

The design matrix was coded as model.matrix(~treatment), with control samples representing the reference