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An important functional difference between these conditions and G6PD deficiency is that the former result from mutations in tissue-specific genes, whereas Gd is a housekeeping gene

Sun J, Lu Z, Deng Y, Wang W, He Q, Yan W, et al

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They suggested that screening children for AN is an effective strategy for identifying adults with prediabetes.[15] Investigations for all overweight adults and children include fasting lipoprotein profile, fasting glucose, hemoglobin, fasting insulin, and alanine aminotransferase

It also highlights individual sensitivity and dose-dependency as modifying factors influencing the intensity of the effects