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It is important in the normal functioning of the nervous system via its role in the synthesis of myelin, and in the circulatory system in the maturation of red blood cells in the bone marrow

Only a small percentage of a standard oral dose is absorbed through this active pathway, and that number drops further when digestion is impaired

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Yan S, Liu H, Yu Y, Han N, Du W

We found that community-dwelling older physically disabled women with metabolically significant vitamin B12 deficiency had a risk of depression that was more than twice as high as that of women without vitamin B12 deficiency