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126 The mechanism by which the rapid dispersal of EAAT2 is regulated in response to increased activity has yet to be elucidated

PLOS ONE 8, e70374

In A-treated astrocytes, KDS12025 significantly reduced H 2 O 2 levels in control pSicoR-scrambled shRNA (Sc-shRNA) astrocytes, but this effect was abolished in Hb-silenced astrocytes, indicating the necessity of Hb for the action of KDS12025 (Fig