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In sum, these ~200 nm iRGDSPNPs exploited transcytosis and tumorcell homing to deliver smallmolecule inhibitors that dismantle key immunosuppressive circuits in GBM

An RCT in 72 patients with NAFLD found that NAC (600 mg twice daily) for 3 months significantly improved liver enzymes (ALT, AST) and markers of oxidative stress compared to control, though it did not significantly improve liver histology on biopsy (Khoshbaten et al., Hepat Mon, 2010) [33]

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HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: novel role of fumarate in regulation of HIF stability

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