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The same team of investigators followed up on this observational study with a double-blind controlled trial where 46 participants were randomized to receive 500 mg vitamin C twice daily or placebo for four weeks

Options include partial reconstitution (if feasible with your vial format), freezing portions of reconstituted solution (accepting some potency loss), or adjusting your dose higher to use everything before expiration

This difference was observed regardless of factors such as sex, age, CRP levels, years since diagnosis, and disease activity and localization

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Supplements containing activated charcoal and copper chlorophyllin are used to lower body odour and gut TMA levels, respectively