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Pseudo-TMA involves intramedullary hemolysis, and laboratory tests show elevated LDH, low haptoglobin, thrombocytopenia, and schistocytes in the peripheral blood smear

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Oxidative cellular dysfunction is caused by highly reactive substances (such as hydrogen peroxide, superoxide, peroxynitrite and hydroxyl radicals) through a variety of mechanisms, such as lipid peroxidation, enzyme inactivation, mitochondrial respiratory chain failure, DNA alteration and/or cell death