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10f-THF: 10-formyltetrahydrofolate 5mTHF: 5-methyltetrahydrofolate AICAR: P-ribosyl-5-amino-4-imidazole carboxamide CH = THF: 5-10-methenyltetrahydrofolate CH2-THF: 5-10-methylenetetrahydrofolate Cys: cysteine Cysta cystathionine DHF: dihydrofolate DMG: dimethylglycine dTMP: deoxythymidine monophosphate dUMP: deoxyuridine monophophate GAR: glycinamide ribonucleotide Glut: glutamate Glut: Cys glutamyl-cysteine Gly: glycine

Finally, regulatory and protective measures must be explored to protect aquatic environments against drug contamination

Repletion plan (scheduled): low B12 or recurring fatigue set a cadence (weekly/bi-weekly/monthly) and adjust based on how you feel and any labs

10.1194/jlr.M800321-JLR200 J Lipid Res

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