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doi: 10.1016/j.pep.2021.105856

Plasmids All shRNA plasmids were purchased from the shRNA library at the Center of Biomedical Analysis, Tsinghua University

Although Hg did not affect CAT2, CAT3, and GR2 , their expression was downregulated by exogenous Cys

[] Figure 8 shows a simplified diagram of glutathione synthesis from the synthetic precursor NAC

demonstrated that arginine deficit can enhance the toxic effects of cyclin-dependent kinase (CDK) inhibitors on GBM cells by impairing mitochondrial metabolism, inducing autophagy, and preventing DNA damage response [116]